Despite the overall low budget nature of this film, the producers obtained the services of the highly regarded cinematographer John Alton. This became one of two features shot by Alton during the final year of his active career. This did not indicate a decline in Alton's professional reputation; the other film shot that year was the far more upscale Elmer Gantry (1960).

The spaceship which lands on the moon is called the Lunar Eagle One. Nine years after this movie was released, the first human visit to the moon was accomplished in a lunar lander called the Eagle.

This film was reportedly shot in 8 days on a budget of $150,000.

The astronauts' acceleration couches were common tube-lined poolside recliners.

The spaceship's communication device is a modified film editing machine (Movieola).

The spaceship's navigation device is a Norden bomb sight, minus the stabilizer base.

This low budget film with limited resources was, rather oddly, paired with Ishirô Honda's elaborate big budget sci-fi spectacle Uchû daisensô (1959) for its first US release.

In the beginning of the film, as the narrator introduces the characters, they are shown walking to the rocket through heavy fog. NASA would never launch a mission in that kind of weather.

NASA landed six missions on the Moon, each with a two-man crew. Therefore, the number of astronauts who eventually did walk on the lunar surface actually is twelve.

On the bridge of the ship, a black timer device hangs on the wall. The device is a common darkroom timer, disguised with a piece of tape to cover the brand name.

This 1960 release was the first U.S. science fiction film to have a spaceship with a multi-racial crew. The East German/Polish production of "The Silent Star"/"First Spaceship on Venus" (1960) with its multi-racial crew beat this to the screen by approximately six months.

This film was parodied by Mystery Science Theater 3000 - Season 5, Episode 24.